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Will develop a global strategy for developing, manufacturing and commercializing eplontersen, an antisense medicine to treat transthyretin amyloidosis.
December 7, 2021
By: Kristin Brooks
Managing Editor, Contract Pharma
Ionis Pharmaceuticals, a leader in RNA-targeted therapies, entered into a strategic collaboration agreement with AstraZeneca to develop and commercialize eplontersen, Ionis’ investigational antisense medicine for the treatment of transthyretin amyloidosis (ATTR). Ionis will receive $200 million upfront, up to $485 million in development and approval milestones, and up to $2.9 billion in milestone payments, as well as royalties. Eplontersen, formerly known as IONIS-TTR-LRx, is desig...
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